the genus of human beings, 1802, in William Turton's translation of Linnæus, coined in Modern Latin from Latin homo "man" (technically "male human," but in logical and scholastic writing "human being;" see homunculus) + sapiens, present participle of sapere "be wise" (see sapient).
Homo as the genus of the human race, within the order Primates, was formally instituted in Modern Latin 1758 by Linnaeus (originally also including chimpanzees). Used since in various Latin or pseudo-Latin combinations intended to emphasize some aspect of humanity, as in Henri Bergson's Homo faber "man the tool-maker" (in "L'Evolution Créatrice", 1907).
late 14c., "type of facial ulcer, lupus," Latin, literally "touch me not," from noli, imperative of nolle "to be unwilling" + me (see me) + tangere "to touch" (from PIE root *tag- "to touch, handle"). Used over the years of various persons or things that must not be touched, especially "picture of Jesus as he appeared to Mary Magdalene" (1670s, see John xx.17) and "plant of the genus Impatiens" (1560s, so called because the ripe seed pods burst when touched).