early 14c., "discomfort, inconvenience, distress, trouble," from Old French desaise "lack, want; discomfort, distress; trouble, misfortune; disease, sickness," from des- "without, away" (see dis-) + aise "ease" (see ease (n.)). Restricted pathological sense of "sickness, illness" in English emerged by late 14c.; the word still sometimes was used in its literal sense early 17c., and was somewhat revived 20c., usually with a hyphen (dis-ease).
early 15c., cronik, of diseases, "lasting a long time," from Old French chronique and directly from Latin chronicus, from Greek khronikos "of time, concerning time," from khronos "time" (see chrono-). Vague disapproving sense (from 17c.) is from association with diseases and later addictions. Literal sense "pertaining to time" is rare in English. As a popular slang catch-all word for "cannabis," popularized from 1992 by "The Chronic," an album released by rapper Dr. Dre; said to be because it described especially potent marijuana, on the notion of "extreme, severe." Related: Chronical; chronically.
mid-14c., disesen, "to make uneasy, trouble; inflict pain," a sense now obsolete; late 14c. as "to have an illness or infection;" late 15c. in the transitive sense of "to infect with a disease, make ill;" from disease (n.). Tyndale (1526) has Thy doughter is deed, disease not the master where KJV has trouble not (Luke viii.49).
"exophthalmic goiter," 1862, named for Irish physician Robert James Graves (1796-1853), who first recognized the disease in 1835. The surname probably is from Old Norse greifi "steward," corresponding to Old English gerefa (see reeve).
form of paralysis, 1877, from French maladie de Parkinson (1876), named for English physician James Parkinson (1755-1824), who described it (1817) under the names shaking palsy and paralysis agitans.
"chronic nephritis," 1831, so called for English physician Richard Bright (1789-1858), who in 1827 first described it.
1877, named for English pathologist Dr. Thomas Hodgkin (1798-1866) who first described it in 1832.
1938, named for Norwegian physician Gerhard Henrik Armauer Hansen (1841-1912) who in 1871 discovered the bacillus that causes it.
" chronic inflammatory condition of the digestive tract," 1935, for U.S. pathologist Burrill Bernard Crohn, one of the team that wrote the article describing it in 1932.
senium præcox, 1912, the title of article by S.C. Fuller published in "Journal of Nervous and Mental Diseases;" named for German neurologist Alois Alzheimer (1864-1915). The disease name was not common before 1970s; shortened form Alzheimer's is recorded from 1954. The surname is from the place name Alzheim, literally "Old Hamlet."