early 15c., cronik, of diseases, "lasting a long time," from Old French chronique and directly from Latin chronicus, from Greek khronikos "of time, concerning time," from khronos "time" (see chrono-). Vague disapproving sense (from 17c.) is from association with diseases and later addictions. Literal sense "pertaining to time" is rare in English. As a popular slang catch-all word for "cannabis," popularized from 1992 by "The Chronic," an album released by rapper Dr. Dre; said to be because it described especially potent marijuana, on the notion of "extreme, severe." Related: Chronical; chronically.
" chronic inflammatory condition of the digestive tract," 1935, for U.S. pathologist Burrill Bernard Crohn, one of the team that wrote the article describing it in 1932.
"chronic non-contagious skin disease characterized by dry, red patches covered with flakes," 1680s, from medical Latin psoriasis, in Late Latin "mange, scurvy," from Greek psōriasis "the itch; a being itchy," from psōrian "to have the itch," from psōra "itch, mange, scab," related to psēn "to rub" (see psilo-). Related: Psoriatic.
"chronic inflammation of connective tissue," originally and especially of the liver, 1827, coined in Modern Latin by French physician René-Théophile-Hyacinthe Laennec with -osis and Greek kirros "red-yellow, yellow-brown, tawny," which is of unknown origin. The form is erroneous, presuming Greek *kirrhos. So called for the orange-yellow appearance of the diseased liver. Related: Cirrhotic.