Etymology
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*per- (1)

Proto-Indo-European root forming prepositions, etc., meaning "forward," and, by extension, "in front of, before, first, chief, toward, near, against," etc.

It forms all or part of: afford; approach; appropriate; approve; approximate; barbican; before; deprive; expropriate; far; first; for; for-; fore; fore-; forefather; foremost; former (adj.); forth; frame; frau; fret; Freya; fro; froward; from; furnish; furniture; further; galore; hysteron-proteron; impervious; improbity; impromptu; improve; palfrey; par (prep.); para- (1) "alongside, beyond; altered; contrary; irregular, abnormal;" paradise; pardon; paramount; paramour; parvenu; pellucid; per; per-; percent; percussion; perennial; perestroika; perfect; perfidy; perform; perfume; perfunctory; perhaps; peri-; perish; perjury; permanent; permeate; permit; pernicious; perpendicular; perpetual; perplex; persecute; persevere; perspective; perspire; persuasion; pertain; peruse; pervade; pervert; pierce; portray; postprandial; prae-; Prakrit; pre-; premier; presbyter; Presbyterian; preterite; pride; priest; primal; primary; primate; primavera; prime; primeval; primitive; primo; primogenitor; primogeniture; primordial; primus; prince; principal; principle; prior; pristine; private; privilege; privy; pro (n.2) "a consideration or argument in favor;" pro-; probably; probe; probity; problem; proceed; proclaim; prodigal; produce; profane; profess; profile; profit; profound; profuse; project; promise; prompt; prone; proof; proper; property; propinquity; prophet; prose; prostate; prosthesis; protagonist; Protean; protect; protein; Proterozoic; protest; proto-; protocol; proton; protoplasm; Protozoa; proud; prove; proverb; provide; provoke; prow; prowess; proximate; Purana; purchase; purdah; reciprocal; rapprochement; reproach; reprove; veneer.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit pari "around, about, through," parah "farther, remote, ulterior," pura "formerly, before," pra- "before, forward, forth;" Avestan pairi- "around," paro "before;" Hittite para "outside of," Greek peri "around, about, near, beyond," pera "across, beyond," paros "before," para "from beside, beyond," pro "before;" Latin pro "before, for, on behalf of, instead of," porro "forward," prae "before," per "through;" Old Church Slavonic pra-dedu "great-grandfather;" Russian pere- "through;" Lithuanian per "through;" Old Irish ire "farther," roar "enough;" Gothic faura "before," Old English fore (prep.) "before, in front of," (adv.) "before, previously," fram "forward, from," feor "to a great distance, long ago;" German vor "before, in front of;" Old Irish air- Gothic fair-, German ver-, Old English fer-, intensive prefixes.

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*ant- 
Proto-Indo-European root meaning "front, forehead," with derivatives meaning "in front of, before; end." Also see *ambhi-.

It forms all or part of: advance; advantage; along; ancestor; ancient (adj.); answer; Antaeus; ante; ante-; ante meridiem; antecede; antecedent; antedate; antediluvian; ante-partum; antepenultimate; anterior; anti-; antic; anticipate; anticipation; antique; antler; avant-garde; elope; end; rampart; un- (2) prefix of reversal; until; vambrace; vamp (n.1) "upper of a shoe or boot;" vanguard.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit antah "end, border, boundary;" Hittite hanti "opposite;" Greek anta, anten "opposite," anti "over against, opposite, before;" Latin ante (prep., adv.) "before (in place or time), in front of, against;" Old Lithuanian anta "on to;" Gothic anda "along;" Old English and- "against;" German ent- "along, against."
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rat-race (n.)

also rat race, 1934 in reference to aviation training, from rat (n.) + race (n.1).

A rat race is ... a simple game of "follow the leader" in fighter planes. The leader does everything he can think of — Immelmanns, loops, snap rolls, and turns, always turns, tighter and tighter. [Popular Science, May 1941]

In the 1930s actual rat races of some sort are frequently mentioned among popular carnival and gambling attractions. Meaning "fiercely competitive struggle," especially to maintain one's position in work or life is by 1939. Rat-run is from 1870 in the sense of "maze-like passages by which rats move about their territory," but originally and usually in a derogatory transferred sense.

[Matthew] Milton was not, at the period we write of [c. 1811], at all in the ring ; for in the following March he was steward of a rat-race, held at a public-house in Shepherd's-market, where four of these "varmin," decorated with different coloured ribands, were started for a sweepstakes, round the clubroom, before a host of sportsmen. ["Sporting Incidents at Home and Abroad," The Sporting Review, May 1848]
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*kwel- (1)
also *kwelə-, Proto-Indo-European root meaning "revolve, move round; sojourn, dwell."

It forms all or part of: accolade; ancillary; atelo-; bazaar; bicycle; bucolic; chakra; chukker; collar; collet; colonial; colony; cult; cultivate; culture; cyclamen; cycle; cyclo-; cyclone; cyclops; decollete; encyclical; encyclopedia; entelechy; epicycle; hauberk; hawse; inquiline; Kultur; lapidocolous; nidicolous; palimpsest; palindrome; palinode; pole (n.2) "ends of Earth's axis;" pulley; rickshaw; talisman; teleology; telic; telophase; telos; torticollis; wheel.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit cakram "circle, wheel," carati "he moves, wanders;" Avestan caraiti "applies himself," c'axra "chariot, wagon;" Greek kyklos "circle, wheel, any circular body, circular motion, cycle of events,"polos "a round axis" (PIE *kw- becomes Greek p- before some vowels), polein "move around;" Latin colere "to frequent, dwell in, to cultivate, move around," cultus "tended, cultivated," hence also "polished," colonus "husbandman, tenant farmer, settler, colonist;" Lithuanian kelias "a road, a way;" Old Norse hvel, Old English hweol "wheel;" Old Church Slavonic kolo, Old Russian kolo, Polish koło, Russian koleso "a wheel."
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*per- (2)

Proto-Indo-European root meaning "to lead, pass over." A verbal root associated with *per- (1), which forms prepositions and preverbs with the basic meaning "forward, through; in front of, before," etc.

It forms all or part of: aporia; asportation; comport; deport; disport; emporium; Euphrates; export; fare; farewell; fartlek; Ferdinand; fere; fern; ferry; firth; fjord; ford; Fuhrer; gaberdine; import; important; importune; opportune; opportunity; passport; porch; pore (n.) "minute opening;" port (n.1) "harbor;" port (n.2) "gateway, entrance;" port (n.3) "bearing, mien;" port (v.) "to carry;" portable; portage; portal; portcullis; porter (n.1) "person who carries;" porter (n.2) "doorkeeper, janitor;" portfolio; portico; portiere; purport; practical; rapport; report; sport; support; transport; warfare; wayfarer; welfare.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit parayati "carries over;" Greek poros "journey, passage, way," peirein "to pierce, pass through, run through;" Latin portare "to carry," porta "gate, door," portus "port, harbor," originally "entrance, passage," peritus "experienced;" Avestan peretush "passage, ford, bridge;" Armenian hordan "go forward;" Old Welsh rit, Welsh rhyd "ford;" Old Church Slavonic pariti "to fly;" Old English faran "to go, journey," Old Norse fjörðr "inlet, estuary."

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