Figurative use in English is from 1775; applied to intense colors from 1916; an acid dye (1888) involves an acid bath. Acid test is American English, 1881, a quick way to distinguish gold from similar metals by application of nitric acid. Acid rain "highly acidity in rain caused by atmospheric pollution" is first recorded 1859 in reference to England. Acid drop as a kind of hard sugar candy flavored with tartaric acid is by 1835, with drop (n.) in the "lozenge" sense.
1690s, from acid (adj.); originally loosely applied to any substance tasting like vinegar, in modern chemistry gradually given more precise definitions from early 18c. Slang meaning "LSD-25" first recorded 1966 (see LSD).
When I was on acid I would see things that looked like beams of light, and I would hear things that sounded an awful lot like car horns. [Mitch Hedberg, 1968-2005, U.S. stand-up comic]
Acid rock (type performed or received by people using LSD) is also from 1966; acid house dance music style is 1988, probably from acid in the hallucinogenic sense + house "dance club DJ music style."
It forms all or part of: acacia; acanthus; accipiter; acer; acerbic; acerbity; acervate; acervulus; acescent; acetic; acid; acicular; acme; acne; acrid; acridity; acrimony; acro-; acrobat; acromegaly; acronym; acrophobia; acropolis; acrostic; acrylic; acuity; aculeate; acumen; acupressure; acupuncture; acute; aglet; ague; Akron; anoxic; awn; coelacanth; dioxin; deoxy-; eager; ear (n.2) "grain part of corn;" edge (n.); egg (v.) "to goad on, incite;" eglantine; epoxy; ester; exacerbation; hammer; hypoxia; mediocre; oxalic; oxide; oxy-; oxygen; oxymoron; paragon; pyracanth; paroxysm; selvage; vinegar.
It is the hypothetical source of/evidence for its existence is provided by: Greek akros "at the end, at the top, outermost; consummate, excellent," akis "sharp point," akros "at the farthest point, highest, outermost," akantha "thorn," akme "summit, edge," oxys "sharp, bitter;" Sanskrit acri- "corner, edge," acani- "point of an arrow," asrih "edge;" Oscan akrid (ablative singular) "sharply;" Latin acer (fem. acris) "sharp to the senses, pungent, bitter, eager, fierce," acutus "sharp, pointed," acuere "to sharpen," acerbus "harsh, bitter," acere "be sharp, be bitter," acus "a needle, pin," ocris "jagged mountain;" Lithuanian ašmuo "sharpness," akstis "sharp stick;" Old Lithuanian aštras, Lithuanian aštrus "sharp;" Old Church Slavonic ostru, Russian óstryj "sharp;" Old Irish er "high;" Welsh ochr "edge, corner, border;" Old Norse eggja "goad;" Old English ecg "sword;" German Eck "corner."