early 14c., "discomfort, inconvenience, distress, trouble," from Old French desaise "lack, want; discomfort, distress; trouble, misfortune; disease, sickness," from des- "without, away" (see dis-) + aise "ease" (see ease (n.)). Restricted pathological sense of "sickness, illness" in English emerged by late 14c.; the word still sometimes was used in its literal sense early 17c., and was somewhat revived 20c., usually with a hyphen (dis-ease).
mid-14c., disesen, "to make uneasy, trouble; inflict pain," a sense now obsolete; late 14c. as "to have an illness or infection;" late 15c. in the transitive sense of "to infect with a disease, make ill;" from disease (n.). Tyndale (1526) has Thy doughter is deed, disease not the master where KJV has trouble not (Luke viii.49).
"exophthalmic goiter," 1862, named for Irish physician Robert James Graves (1796-1853), who first recognized the disease in 1835. The surname probably is from Old Norse greifi "steward," corresponding to Old English gerefa (see reeve).
form of paralysis, 1877, from French maladie de Parkinson (1876), named for English physician James Parkinson (1755-1824), who described it (1817) under the names shaking palsy and paralysis agitans.
"chronic nephritis," 1831, so called for English physician Richard Bright (1789-1858), who in 1827 first described it.
1877, named for English pathologist Dr. Thomas Hodgkin (1798-1866) who first described it in 1832.
1938, named for Norwegian physician Gerhard Henrik Armauer Hansen (1841-1912) who in 1871 discovered the bacillus that causes it.
" chronic inflammatory condition of the digestive tract," 1935, for U.S. pathologist Burrill Bernard Crohn, one of the team that wrote the article describing it in 1932.
senium præcox, 1912, the title of article by S.C. Fuller published in "Journal of Nervous and Mental Diseases;" named for German neurologist Alois Alzheimer (1864-1915). The disease name was not common before 1970s; shortened form Alzheimer's is recorded from 1954. The surname is from the place name Alzheim, literally "Old Hamlet."
early 15c., "eccentric circle or orbit," originally a term in Ptolemaic astronomy, "circle or orbit not having the Earth precisely at its center," from French eccentrique and directly from Medieval Latin eccentricus (noun and adjective), from Greek ekkentros "out of the center" (as opposed to concentric), from ek "out" (see ex-) + kentron "center" (see center (n.)). Meaning "odd or whimsical person" is attested by 1817 (S.W. Ryley, "The Itinerant, or Memoirs of an Actor").
June 4 .—Died in the streets in Newcastle, William Barron, an eccentric, well known for many years by the name of Billy Pea-pudding. [John Sykes, "Local Records, or Historical Register of Remarkable Events which have Occurred Exclusively in the Counties of Durham and Northumberland, Town and County of Newcastle Upon Tyne, and Berwick Upon Tweed," Newcastle, 1824]