early 15c., manumitten, "set (a slave or captive) free," from Latin manumittere "to release from one's power, set at liberty, emancipate," literally "to send from one's 'hand'" (i.e. "control"), from the phrase manu mittere "release from control," from manu, ablative of manus "power of a master," literally "hand" (from PIE root *man- (2) "hand") + mittere "let go, release" (see mission). Related: Manumitted; manumitting. Alternative form manumiss, manumise was sometimes used 16c.-19c.
It forms all or part of: amanuensis; command; commando; commend; countermand; demand; Edmund; emancipate; legerdemain; maintain; manacle; manage; manciple; mandamus; mandate; manege; maneuver; manicure; manifest; manipulation; manner; manque; mansuetude; manual; manubrium; manufacture; manumission; manumit; manure; manuscript; mastiff; Maundy Thursday; mortmain; Raymond; recommend; remand; Sigismund.
It is the hypothetical source of/evidence for its existence is provided by: Hittite maniiahh- "to distribute, entrust;" Greek mane "hand," Latin manus "hand, strength, power over; armed force; handwriting," mandare "to order, commit to one's charge," literally "to give into one's hand;" Old Norse mund "hand," Old English mund "hand, protection, guardian," German Vormund "guardian;" Old Irish muin "protection, patronage."