early 14c., "discomfort, inconvenience, distress, trouble," from Old French desaise "lack, want; discomfort, distress; trouble, misfortune; disease, sickness," from des- "without, away" (see dis-) + aise "ease" (see ease (n.)). Restricted pathological sense of "sickness, illness" in English emerged by late 14c.; the word still sometimes was used in its literal sense early 17c., and was somewhat revived 20c., usually with a hyphen (dis-ease).

mid-14c., disesen, "to make uneasy, trouble; inflict pain," a sense now obsolete; late 14c. as "to have an illness or infection;" late 15c. in the transitive sense of "to infect with a disease, make ill;" from disease (n.). Tyndale (1526) has Thy doughter is deed, disease not the master where KJV has trouble not (Luke viii.49).

"exophthalmic goiter," 1862, named for Irish physician Robert James Graves (1796-1853), who first recognized the disease in 1835. The surname probably is from Old Norse greifi "steward," corresponding to Old English gerefa (see reeve).

form of paralysis, 1877, from French maladie de Parkinson (1876), named for English physician James Parkinson (1755-1824), who described it (1817) under the names shaking palsy and paralysis agitans.

"chronic nephritis," 1831, so called for English physician Richard Bright (1789-1858), who in 1827 first described it.

1877, named for English pathologist Dr. Thomas Hodgkin (1798-1866) who first described it in 1832.

1938, named for Norwegian physician Gerhard Henrik Armauer Hansen (1841-1912) who in 1871 discovered the bacillus that causes it.