Etymology
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hypo- 
word-forming element meaning "under, beneath; less, less than" (in chemistry, indicating a lesser oxidation), from Greek hypo (prep. and adverb) "under, beneath; up from under; toward and under (i.e. into)," from PIE root *upo "under."
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kh- 
used to represent sounds not native to English, more or less resembling an aspirated "k," in transliterations from Arabic, Turkish, Russian, etc.
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chiro- 

less properly cheiro-, before vowels chir-, word-forming element meaning "hand," from Latinized form of Greek kheiro-, combining form of kheir (genitive kheiros) "the hand," from PIE root *ghes- "hand."

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mis- (2)

word-forming element of Latin origin (in mischief, miscreant, misadventure, misnomer, etc.), from Old French mes- "bad, badly, wrong, wrongly," from Vulgar Latin *minus-, from Latin minus "less" (from suffixed form of PIE root *mei- (2) "small"), which was not used as a prefix in Latin but in the Romanic languages was affixed to words as a depreciative or negative element. The form in French perhaps was influenced in Old French by *miss-, the Frankish (Germanic) form of mis- (1).

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un- (2)
prefix of reversal, deprivation, or removal (as in unhand, undo, unbutton), Old English on-, un-, from Proto-Germanic *andi- (source also of Old Saxon ant-, Old Norse and-, Dutch ont-, Old High German ant-, German ent-, Gothic and- "against"), from PIE *anti "facing opposite, near, in front of, before, against" (from PIE root *ant- "front, forehead," with derivatives meaning "in front of, before").

More or less confused with un- (1) through similarity in the notions of "negation" and "reversal;" an adjective such as unlocked might represent "not locked" (un- (1)) or the past tense of unlock (un- (2)).
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