Etymology
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in- (2)
Origin and meaning of in-

element meaning "into, in, on, upon" (also im-, il-, ir- by assimilation of -n- with following consonant), from Latin in- "in," from PIE root *en "in."

In Old French (and hence in Middle English) this often became en-, which in English had a strong tendency to revert to Latin in-, but not always, which accounts for pairs such as enquire/inquire. There was a native form, which in West Saxon usually appeared as on- (as in Old English onliehtan "to enlighten"), and some of those verbs survived into Middle English (such as inwrite "to inscribe"), but all now seem to be extinct.

Not related to in- (1) "not," which also was a common prefix in Latin, causing confusion: to the Romans impressus could mean "pressed" or "unpressed;" inaudire meant "to hear," but inauditus meant "unheard of;" in Late Latin investigabilis could mean "that may be searched into" or "that cannot be searched into." Latin invocatus was "uncalled, uninvited," but invocare was "to call, appeal to."

The trouble has continued in English; the hesitation over what is meant by inflammable being a commonly cited example. Implume (1610s) meant "to feather," but implumed (c. 1600) meant "unfeathered." Impliable can mean "capable of being implied" (1865) or "inflexible" (1734). Impartible in 17c. could mean "incapable of being divided" or "capable of being imparted." Impassionate can be "free from passion" or it can mean "strongly stirred by passion." Inanimate (adj.) is "lifeless," but Donne uses inanimate (v.) to mean "infuse with life or vigor." Irruption is "a breaking in," but irruptible is "unbreakable."

In addition to improve "use to one's profit," Middle English also had a verb improve meaning "to disprove" (15c.). To inculpate is "to accuse," but inculpable means "not culpable, free from blame." Infestive has meant "troublesome, annoying" (1560s, from infest) and "not festive" (1620s). In Middle English inflexible could mean "incapable of being bent" or "capable of being swayed or moved." In 17c., informed could mean "current in information," formed, animated," or "unformed, formless" ("This was an awkward use" [OED]). Inhabited has meant "dwelt in" (1560s) and "uninhabited" (1610s); inhabitable likewise has been used on opposite senses, a confusion that goes back to Late Latin.

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spirit (n.)
Origin and meaning of spirit

mid-13c., "animating or vital principle in man and animals," from Anglo-French spirit, Old French espirit "spirit, soul" (12c., Modern French esprit) and directly from Latin spiritus "a breathing (respiration, and of the wind), breath; breath of a god," hence "inspiration; breath of life," hence "life;" also "disposition, character; high spirit, vigor, courage; pride, arrogance," related to spirare "to breathe," perhaps from PIE *(s)peis- "to blow" (source also of Old Church Slavonic pisto "to play on the flute"). But de Vaan says "Possibly an onomatopoeic formation imitating the sound of breathing. There are no direct cognates."

Meaning "supernatural immaterial creature; angel, demon; an apparition, invisible corporeal being of an airy nature" is attested from mid-14c.; from late 14c. as "a ghost" (see ghost (n.)). From c. 1500 as "a nature, character"; sense of "essential principle of something" (in a non-theological context, as in Spirit of St. Louis) is attested from 1680s, common after 1800; Spirit of '76 in reference to the qualities that sparked and sustained the American Revolution is attested by 1797 in William Cobbett's "Porcupine's Gazette and Daily Advertiser."

From late 14c. in alchemy as "volatile substance; distillate;" from c. 1500 as "substance capable of uniting the fixed and the volatile elements of the philosopher's stone." Hence spirits "volatile substance;" sense narrowed to "strong alcoholic liquor" by 1670s. This also is the sense in spirit level (1768). Also from mid-14c. as "character, disposition; way of thinking and feeling, state of mind; source of a human desire;" in Middle English freedom of spirit meant "freedom of choice." From late 14c. as "divine substance, divine mind, God;" also "Christ" or His divine nature; "the Holy Ghost; divine power;" also, "extension of divine power to man; inspiration, a charismatic state; charismatic power, especially of prophecy." Also "essential nature, essential quality." From 1580s in metaphoric sense "animation, vitality."

According to Barnhart and OED, originally in English mainly from passages in Vulgate, where the Latin word translates Greek pneuma and Hebrew ruah. Distinction between "soul" and "spirit" (as "seat of emotions") became current in Christian terminology (such as Greek psykhe vs. pneuma, Latin anima vs. spiritus) but "is without significance for earlier periods" [Buck]. Latin spiritus, usually in classical Latin "breath," replaces animus in the sense "spirit" in the imperial period and appears in Christian writings as the usual equivalent of Greek pneuma. Spirit-rapping is from 1852.

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