"tough outer membrane surrounding the brain and the spinal cord," c. 1400, from Medieval Latin dura mater cerebri, literally "hard mother of the brain," a loan-translation of Arabic umm al-dimagh as-safiqa, literally "thick mother of the brain." "In Arabic, the words 'father,' 'mother,' and 'son' are often used to denote relationships between things" [Klein].
1590s, "type of shellfish that yields mother-of-pearl," from French nacre (Old French nacaire, 14c.), from Italian naccaro (now nacchera), possibly from Arabic naqur "hunting horn" (from nakara "to hollow out"), in reference to the shape of the mollusk shell. Meaning "mother-of-pearl" is from 1718. The French adjectival form nacré was applied in English to decorative objects iridescent like mother of pearl (1895).