Etymology
Advertisement
unrefined (adj.)
1590s, "not refined in manners," from un- (1) "not" + past participle of refine (v.). Meaning "not free from gross matter" is recorded from 1610s.
Related entries & more 
Advertisement
uninformed (adj.)
1590s, from un- (1) "not" + past participle of inform. Originally in reference to some specific matter or subject; general sense of "uneducated, ignorant" is recorded from 1640s.
Related entries & more 
biolysis (n.)
1865, "the destruction of life," later more specifically "dissolution of a living organism, resolution of a dead organism into its constituent matter" (1880s); see bio- + -lysis. Related: Biolytic.
Related entries & more 
constipated (adj.)

"having difficulty evacuating the bowels while they are filled or crammed with fecal matter," 1530s, past-participle adjective from constipate (v.).

Related entries & more 
mispunctuate (v.)

"punctuate (written matter) erroneously or incorrectly," by 1843, from mis- (1) "badly, wrongly" + punctuate (v.). Related: Mispunctuated; mispunctuating; mispunctuation (1812).

Related entries & more 
Advertisement
sick (n.)

"those who are sick, persons suffering from illness," Old English seoce, from the source of  sick (adj.). Colloquial sense of "vomited matter" is by 1959.

Related entries & more 
materially (adv.)

late 14c., "with, in, by, or with reference to matter or material things," from material (adj.) + -ly (2). Sense of "to an important extent or degree, essentially" is from 1650s.

Related entries & more 
hereabout (adv.)
"about this, with regard to this matter," c. 1200, from here + about. Meaning "in the vicinity, near here" is from early 13c. Hereabouts, with adverbial genitive -s-, is from 1580s.
Related entries & more 
vaccine (n.)
"matter used in vaccination," 1846, from French vaccin, noun use of adjective, from Latin vaccina, fem. of vaccinus "pertaining to a cow" (see vaccination). Related: Vaccinal; vaccinic.
Related entries & more 
whatever (pron.)

mid-14c., "what in the world," emphatic of what, with ever. From late 14c. as "anything at all; all of; no matter what or who." From late 14c. as an adjective, "any sort of, any, every; no matter what, regardless of what." From 1870 as "whatever may be the cause, at any event," which could be the source of the modern teen slang dismissive use, which Partridge dates to 1989.

Related entries & more 

Page 5