c. 1600, "the great world" (the universe, as distinct from the "little world" of man and human societies), from French macrocosme (c. 1300) and directly from Medieval Latin macrocosmus, from Greek makros "large, long" (from PIE root *mak- "long, thin") + kosmos "world," also "order, harmonious arrangement" (see cosmos). Compare microcosm. The concept, if not the word, generally is traced to Democritus (5c. B.C.E.). Related: Macrocosmic.
late 12c., mycrocossmos (modern form from early 15c.), "human nature, man viewed as the epitome of creation," literally "miniature world" (applied metaphorically to the human frame by philosophers, hence a favorite word with medieval writers to signify "a man"), from Medieval Latin microcosmus, from Greek mikros "small" (see micro-) + kosmos "world" (see cosmos).
General sense of "a community constituting a world unto itself, a little society" is attested from 1560s, perhaps from French microcosme. A native expression in the same sense was petty world (c. 1600).
Forrþi mahht tu nemmnenn mann Affterr Grikkishe spæche Mycrocossmos, þat nemmnedd iss Affterr Ennglisshe spæche Þe little werelld. ["Ormulum," c. 1175]
And the Anglo-Saxon glossaries have læsse middaneard.
1690s, "a theory of the creation;" 1766 as "the creation of the universe;" 1777 as "science of the origin of the universe," from Latinized form of Greek kosmogonia "creation of the world," from kosmos "world, universe" (see cosmos) + -gonia "a begetting," from gonos "birth" (from PIE root *gene- "give birth, beget"). Related: Cosmogonal; cosmogonic; cosmogonist.
"very much, extreme," 1979, from Italian mondo "world" (from Latin mundus; see mundane); specifically from "Mondo cane," title of a 1961 film, literally "world for a dog" (English title "A Dog's Life"), depicting eccentric human behavior. The word was abstracted from the title and taken as an intensifier.