Etymology
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great- 

word-forming element denoting "kinship one degree further removed," early 15c. (in great uncle), from great (adj.), based on similar use of French grand (see grand-). An Old English way of saying "great-grandfather" was þridda fæder, literally "third father;" in early Middle English furþur ealdefader was used (12c.).

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holo- 

before vowels, hol-, word-forming element meaning "whole, entire, complete," from Greek holos "whole, entire, complete," also "safe and sound;" as a noun, "the universe," as an adverb, "on the whole;" from PIE *sol-wo-, from root *sol- "whole." Often translated as whole, which it resembles but with which it apparently has no etymological connection.

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piezo- 

word-forming element meaning "pressure," from Greek piezein "to press tight, squeeze," from PIE *pisedyo- "to sit upon" (source also of Sanskrit pidayati "presses, oppresses"), from *pi "on," short for *epi (see epi-) + root *sed- (1) "to sit." First in piezometer (1820), an instrument for ascertaining or testing pressure. It was in common use in word formation from c. 1900.

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extra- 

word-forming element meaning "outside; beyond the scope of; in addition to what is usual or expected," in classical Latin recorded only in extraordinarius, but more used in Medieval Latin and modern formations; it represents Latin extra (adv.) "on the outside, without, except," the old fem. ablative singular of exterus "outward, outside," comparative of ex "out of" (see ex-).

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se- 

word-forming element in words of Latin origin, "apart, away," from Latin se-, collateral form of sed- "without, apart, aside," probably originally "by one's self, on one's own," and related to sed, Latin reflexive pronoun (accusative and ablative), from PIE *sed-, extended form of root *s(w)e-, pronoun of the third person and reflexive (source also of German sich; see idiom).

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infra- 

word-forming element meaning "below, beneath," from Latin infra (adverb and preposition) "below, underneath, on the under side, beneath," also "later than; smaller than; inferior to," related to infernus "low, below," from PIE *ndher "under" (source also of Sanskrit adnah "below," Old English under "under, among;" see under). Modern popular use of it dates from the 1920s, as an opposite to super-, often in science fiction. "This use of infra- is scarcely a Latin one" [OED].

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circum- 

word-forming element meaning "around, round about, all around, on all sides," from Latin adverb and preposition circum "around, round about," literally "in a circle," probably accusative form of circus "ring" (see circus). The Latin word was commonly used in word-formation. In French, the element became circon-; Kitchin points out that con for cum is common even in classical Latin. For sense development, compare German rings "around."

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super- 

word-forming element meaning "above, over, beyond," from Latin super (adverb and preposition) "above, over, on the top (of), beyond, besides, in addition to," from *(s)uper-, variant form of PIE root *uper "over." In English words from Old French, it appears as sur-. The primary sense seems to have shifted over time from usually meaning "beyond" to usually meaning "very much," which can be contradictory. E.g. supersexual, which is attested from 1895 as "transcending sexuality," from 1968 as "very sexual."

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anti- 

word-forming element of Greek origin meaning "against, opposed to, opposite of, instead," shortened to ant- before vowels and -h-, from Old French anti- and directly from Latin anti-, from Greek anti (prep.) "over, against, opposite; instead, in the place of; as good as; at the price of; for the sake of; compared with; in opposition to; in return; counter-," from PIE *anti "against," also "in front of, before" (from root *ant- "front, forehead," with derivatives meaning "in front of, before"), which became anti- in Italian (hence antipasto) and French.

It is cognate with Sanskrit anti "over, against," and Old English and- (the first element in answer). A common compounding element in Greek, in some combinations it became anth- for euphonic reasons. It appears in some words in Middle English but was not commonly used in English word formations until modern times. In a few English words (anticipate, antique) it represents Latin ante.

In noun compounds where it has the sense of "opposed to, opposite" (Antichrist, anti-communist) the accent remains on the anti-; in adjectives where it retains its old prepositional sense "against, opposed to," the accent remains on the other element (anti-Christian, anti-slavery).

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un- (2)

prefix of reversal, deprivation, or removal (as in unhand, undo, unbutton), Old English on-, un-, from Proto-Germanic *andi- (source also of Old Saxon ant-, Old Norse and-, Dutch ont-, Old High German ant-, German ent-, Gothic and- "against"), from PIE *anti "facing opposite, near, in front of, before, against" (from PIE root *ant- "front, forehead," with derivatives meaning "in front of, before").

More or less confused with un- (1) through similarity in the notions of "negation" and "reversal;" an adjective such as unlocked might represent "not locked" (un- (1)) or the past tense of unlock (un- (2)).

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