The extension of the sense to corresponding relationships of descent, "a generation younger than" (grandson, granddaughter) is from Elizabethan times. The inherited PIE root, *nepot- "grandchild" (see nephew) has shifted to "nephew; niece" in English and other languages (Spanish nieto, nieta). Old English used suna sunu ("son's son"), dohtor sunu ("son's daughter").
word-forming element used in making names for very small units of measure, 1915 (formally adopted as a scientific prefix meaning "one trillionth" by the International System of Units, 1960), from Spanish pico "a little over, a small balance," literally "sharp point, beak," a word of Celtic origin (compare Gaulish beccus "beak").
Middle English and Anglo-French perfective prefix, corresponding to Old French por-, pur- (Modern French pour), from Vulgar Latin *por-, a variant of Latin pro "before, for" (see pro-). This is the earliest form of the prefix in English, and it is retained in some words, but in others it has been corrected to Latinate pro-.
word-forming element meaning "killer," from French -cide, from Latin -cida "cutter, killer, slayer," from -cidere, combining form of caedere "to strike down, chop, beat, hew, fell, slay," from Proto-Italic *kaid-o-, from PIE root *kae-id- "to strike." For Latin vowel change, see acquisition. The element also can represent "killing," from French -cide, from Latin -cidium "a cutting, a killing."
before vowels seism-, word-forming element meaning "earthquake," from Greek seismos "a shaking, shock; an earthquake," also "an extortion" (compare colloquial shake (someone) down), from seiein "to shake, agitate, sway; to quake, shiver" from PIE root *twei- "to agitate, shake, toss; excite; sparkle" (source also of Sanskrit tvesati "to excite; to be excited, inflame, sparkle" and words in Avestan for "fears" and "fright, danger").
Etymologically, a stepfather or stepmother is one who becomes father or mother to an orphan, but the notion of orphanage faded in 20c. and came to denote simply relation through marriage. For sense evolution, compare Latin privignus "stepson," related to privus "deprived." Compare orphan (n.).
before vowels chaet-, word-forming element meaning "hair," also, in scientific use, "spine, bristle," from Latinized form of Greek khaite "long, loose, flowing hair" (of persons, also of horses, lions), from an old PIE word for "hair, mane," source also of Avestan gaesa- "curly hair," gaesu- "'curly haired," Modern Persian ges "hair that hangs down, curls;" Middle Irish gaiset "bristly hair."
The "sh" sound did not exist in Old French, therefore French scribes after the Norman conquest often represented it with -ssh- in medial and final positions, and sch- in initial positions (schape, schamful, schaft for shape, shameful, shaft). But the spelling -sh- has been standard since Caxton, probably as a worn-down form of Middle English -sch-.
In some East Anglian texts from 14c.-15c., x- is used (xal, xulde for shall, should), which would have given the language a very different look had it prevailed, but the London-based sh- ended up as the standard form. The same Germanic sound has become, by natural evolution, modern German and Dutch sch-, Scandinavian sk-.