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meshuga (adj.)
Related entries & more "mad, crazy, stupid," 1892, from Hebrew meshugga, participle of shagag "to go astray, wander." The adjective has forms meshugener, meshugenah before a noun.
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demented (adj.)
Related entries & more "having lost the normal use of reason, afflicted with dementia," 1640s, from obsolete dement "drive mad." Related: Dementedness.
erotomaniac (n.)"one driven mad by passionate love" (sometimes also used in the sense of "nymphomaniac"), 1858, from erotomania.
Related entries & more estrus (n.)1850, "frenzied passion," from Latin oestrus "frenzy, gadfly," from Greek oistros "gadfly; breeze; sting; anything which makes one mad, mad impulse," perhaps from a PIE *eis- (1), forming words denoting passion (see ire). First attested 1890 with specific meaning "rut in animals, sexual heat." Earliest use in English (1690s) was for "a gadfly." Related: Estrous (1900).
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dippy (adj.)
Related entries & more "mad, insane, crazy," especially in love, 1903, perhaps from dip + -y (2), but the exact signification is unclear. Another theory connects it with dipsomania.