also life-blood, 1580s, "blood necessary for life," from life (n.) + blood (n.). Figurative and transferred use for "that which is essential to the life or strength of, that which gives vitality to" is from 1590s.

"life-science," 1957, from bio- "life" + science.

early 15c., "as far as essential qualities or facts are concerned;" from virtual + -ly (2). Sense of "in effect, as good as" is recorded from c. 1600.

also bio-chemistry, "the chemistry of life," 1857, from bio- "life" + chemistry.

also life-span, 1918, from life (n.) + span (n.1).

also life-long, "continuing a lifetime," 1855, from life (n.) + long (adj.).

1840, "right to the present time," from phrase up to date, probably originally from bookkeeping. As an adjective from 1865. Meaning "having the latest facts" is recorded from 1889; that of "having current styles and tastes" is from 1891.

also wild life, "fauna of a region," 1879, from wild (adj.) + life.

also bio-chemist, "student of the chemistry of life," 1894; see bio- "life" + chemist.

also mid-life, 1837, from mid (adj.) + life. Middle-life is from early 14c. Midlife crisis "transition of identity and self-confidence that can occur in middle-aged individuals" is attested by 1965 (crisis of mid-life is by 1963).