Etymology
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irreputable (adj.)
"disreputable," 1709, from assimilated form of in- (1) "not, opposite of" + reputable.
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irresistance (n.)
1640s, from assimilated form of in- "not, opposite of" (see in- (1)) + resistance.
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irresistible (adj.)
1590s, from Late Latin irresistibilis, from assimilated form of in- "not, opposite of" (see in- (1)) + resistere (see resist). Related: Irresistibly; irresistibility.
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irresolute (adj.)
"not firm in purpose, wavering, given to doubt or hesitation," 1570s, from Latin irresolutus "not loosed, not loosened," from assimilated form of in- "not, opposite of" (see in- (1)) + resolutus (see resolute). Related: Irresolutely.
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irresolution (n.)
1590s, from assimilated form of in- (1) "not, opposite of" + resolution. Perhaps from or based on French irrésolution (16c.).
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irresolvable (adj.)
1650s, "insoluble," from assimilated form of in- (1) "not, opposite of" + resolvable. Meaning "that cannot be resolved into parts" is from 1785. Related: Irresolvably.
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irrespective (adj.)
1620s (implied in irrespectively), "disrespectful," from assimilated form of in- (1) "not, opposite of" + respective in its sense of "regardful." Meaning "without taking account of particular circumstances or conditions" had developed by 1690s, from the notion of "not observing or noting with attention." In modern use it tends to be adverbial, in irrespective of, a use attested by c. 1800.
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irresponsible (adj.)
1640s, "not legally answerable for conduct or actions," from assimilated form of in- (1) "not, opposite of" + responsible. Meaning "not acting with a sense of responsibility" is from 1680s. Related: Irresponsibly.
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irresponsive (adj.)
"not responsive, not answering," 1797, from assimilated form of in- "not, opposite of" + responsive.
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