"calm, quiet, placid," usually of persons or temperaments, 1660s, from Latin sedatus "composed, moderate, quiet, tranquil," past participle of sedare "to settle, make calm," causative of sedere "to sit" (from PIE root *sed- (1) "to sit"). Related: Sedately; sedateness (1640s).

1640s, "a musical performance at night in open air" (especially "one given by a lover under the window of his lady" [OED]), from French sérénade (16c.), from Italian serenata "an evening song," literally "calm sky," from sereno "the open air," noun use of sereno "clear, calm," from Latin serenus "peaceful, calm, serene" (see serene (adj.)). The sense was influenced by Italian sera "evening" (from Latin sera, fem. of serus "late"). The meaning "piece of instrumental music suitable for a serenade" is attested from 1728.

early 15c. (Chauliac), sedacioun, "act or process of alleviation of pain;" 1540s, "act of making calm," from French sédation and directly from Latin sedationem (nominative sedatio) "a quieting, assuaging, a calming," noun of action from past-participle stem of sedare "to settle, make calm," causative of sedere "to sit" (from PIE root *sed- (1) "to sit").

1906, of persons, "calm, serene," from Latinized form of Greek ataraktos "not disturbed" (see ataraxia) + -ic. From 1955 of drugs, "inducing calmness."

1590s, of persons, "free from passions, calm, disposed;" 1640s, "not dictated by passion, impartial;" from dis- "the opposite of" + passionate. Related: Dispassionately.

"tranquility, peacefulness, quietness," 1610s, from Latin placiditatem (nominative placiditas), from placidus "peaceful, quiet, gentle, calm" (see placid).

"A normally calm person who has become suddenly enraged or violent" [OED], 1932, from French mouton enragé, literally "angry sheep." See mutton + enrage.