1830 as the name of a children's game (OED describes it as "all-fours" when played for seven "chalks"); with capital initials, as the proprietary name of a brand of carbonated drink, it is attested from 1928.
"adjustments made to an automobile to improve its working," 1911, from verbal phrase tune up "bring to a state of effectiveness," 1718, in reference to musical instruments, from tune (v.) + up (adv.). Attested from 1901 in reference to engines. Meaning "event that serves as practice for a later one" is from 1934, U.S. sports jargon.
also cleanup, 1856, "act of cleaning up, a general cleaning," from clean + up. Meaning "a profit" is recorded from 1878. Verbal phrase clean up "make a large profit" is from 1929. The adjective, in the baseball sense, is recorded by 1910 in reference to the hitter who bats fourth in the lineup: His job is to drive in runs by scoring the players who hit before him and thus "clean up" the bases.
"clever, alert," 1926, from warning cry "heads up!" (i.e. "look up!"). As a noun, "a notification, a warning," by 1988.