"feel regret," Old English hreowan "make sorry, distress, grieve" (class II strong verb; past tense hreaw, past participle hrowen), from Proto-Germanic *khrewanan (cf. Old Frisian riowa, Middle Dutch rouwen, Old Dutch hrewan, German reuen); in part, blended with Old English weak verb hreowian "feel pain or sorrow," and perhaps influenced by Old Norse hryggja "make sad," both from Proto-Germanic *khruwjanan, from the same root; from PIE root *kreue- (2) "to push, strike" (see anacrusis). Related: Rued; ruing.
"perennial evergreen shrub," late 14c., from Old French rue, earlier rude, from Latin ruta "rue," probably from Greek rhyte, of uncertain etymology, originally a Peloponnesian word. The bitter taste of its leaves led to many punning allusions to the noun form of rue (v.).