c.1300, from O.Fr. ire (11c.), from L. ira "anger, wrath, rage," from PIE base *eis-, forming various words denoting "passion" cf. Gk. hieros "filled with the divine, holy," oistros "gadfly," originally "thing causing madness;" Skt. esati "drives on," yasati "boils;" Avestan aesma "anger").