- hypochondria
- 1839, "illness without a specific cause," earlier (1668) "depression or melancholy without real cause," earlier still (1373) ypocandria "upper abdomen," from L.L. hypochondria "the abdomen," from Gk. hypochondria (neut. pl.), from hypo- "under" (see sub-) + chondros "cartilage" (of the breastbone). Reflecting ancient belief that the viscera of the hypochondria were the seat of melancholy. Hypochondriac (n.) in modern sense first recorded 1888.