late 14c., "ancient Roman settlement outside Italy," from L. colonia "settled land, farm, landed estate," from colonus "husbandman, tenant farmer, settler in new land," from colere "to inhabit, cultivate, frequent, practice, tend, guard, respect," from PIE base *kwel- "move around" (source of L. -cola "inhabitant;" see cycle). Also used by the Romans to translate Gk. apoikia "people from home." Modern application dates from 1540s.