1650s, from Gk. kakophonia, from kakophonos "harsh sounding," from kakos "bad, evil" + phone "voice" (see fame). Kako- was a common prefix in Gk., and has often crossed over into Eng., e.g. cacography, the opposite of calligraphy (q.v.). Etymologists connect it with PIE *kakka- "to defecate." Related: Cacophonous (1797).