O.E. bisignisse (Northumbrian) "care, anxiety," from bisig "careful, anxious, busy, occupied" (see busy) + -ness. Sense of "work, occupation" is first recorded late 14c. Sense of "trade, commercial engagements" is first attested 1727. Modern two-syllable pronunciation is 17c. Business card first attested 1840; business letter from 1766.