1770, "severe homesickness" (considered as a disease), Mod.L. (cf. Fr. nostalgie, 1802), coined 1668 by Johannes Hofer as a rendering of Ger. heimweh, from Gk. nostos "homecoming" + algos "pain, grief, distress" (see -algia). Transferred sense (the main modern one) of "wistful yearning for the past" first recorded 1920.
variation of Madeline. The kind of small, rich confection is attested from 1845, named for Madeleine Paulmier, 19c. Fr. pastry cook; any use with a sense of "small thing that evokes powerful nostalgia" is due to Proust (1922).