agnostic Look up agnostic at Dictionary.com
1870, "one who professes that the existence of a First Cause and the essential nature of things are not and cannot be known." Coined by T.H. Huxley (1825-1895) from Gk. agnostos "unknown, unknowable," from a- "not" + gnostos "(to be) known" (see gnostic). Sometimes said to be a reference to Paul's mention of the altar to "the Unknown God," but according to Huxley it was coined with ref. to the early Church movement known as Gnosticism (see Gnostic).
"I ... invented what I conceived to be the appropriate title of 'agnostic,' ... antithetic to the 'Gnostic' of Church history who professed to know so much about the very things of which I was ignorant." [T.H. Huxley, "Science and Christian Tradition," 1889]
The adj. is first recorded 1873. Agnosticism also is recorded from 1870.