"Knocked up in the United States, amongst females, the phrase is equivalent to being enciente, so that Englishmen often unconsciously commit themselves when amongst our Yankee cousins." [John Camden Hotten, "The Slang Dictionary," London, 1860]"The distance between the knots on the log-line should contain 1/120 of a mile, supposing the glass to run exactly half a minute." [Jorge Juan and Antonio de Ulloa, "A Voyage to South America" 1760]The verb meaning "to tie in a knot" is from 1547. Knot-hole is from 1726. Knothead "stupid person" is from 1940.