Thy sharpe and sulpherous bolt Splits the vn-wedgable and gnarled Oke. ["Measure for Measure," II.ii.116]OED and Barnhart call it a variant of knurled, from Middle English knar "knot in wood" (late 14c.), originally "a rock, a stone;" of uncertain origin. "(Gnarled) occurs in one passage of Shakes. (for which the sole authority is the folio of 1623), whence it came into general use in the nineteenth century" [OED].
The gnatte is a litil fflye, and hatte culex..he soukeþ blood and haþ in his mouþ a pipe, as hit were a pricke..And is a-countid a-mong volatiles..and greueþ slepinge men wiþ noyse & wiþ bytinge and wakeþ hem of here reste. [John of Trevisa, transl. of Bartholomew de Glanville's "De proprietatibus rerum," 1398]